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Nordic Biomarker is proud to offer the most complete and flexible portfolio of OEM-reagents for coagulation diagnostics on the market. Strengthen your brand name and expand your business by completing your portfolio with our high quality reagents.


Clotting assays

PT Quick

PT Quick is commonly used for determination of PT in patients administered vitamin K-antagonists and for detection of deficiencies within the extrinsic and common pathways of the coagulation cascade. PT Quick reagent is easy to reconstitute, and calcium is already added to the reagent before lyophilisation.

PT Owren

PT Owren measures the prothrombin time, based on the activity of the vitamin K-dependent coagulation factors; FII, FVII and FX, specifically. PT Owren can be used to monitor warfarin therapy and to evaluate the function of the extrinsic pathway of the coagulation cascade.

APTT

Activated partial thromboplastin time (APTT) is a commonly used screening test for haemostatic defects in the intrinsic and common pathway of the coagulation cascade, as well as the contact activation system. Thus, FII, FV, FVIII, FIX, FX, FXI, FXII, prekallikrein and high-molecular weight kininogen deficiencies can result in a prolonged APTT.

Fib Clauss

Fib Clauss is a functional clotting assay used for quantification of fibrinogen in citrated plasma. Fib Clauss reagent utilises the Clauss technique, where a high concentration of thrombin is added to pre-diluted plasma and the clotting time is measured. The clotting time depends on the level of functional fibrinogen in the sample. Fib Clauss reagent has a large linear range, up to 8 g/L, limiting the number of re-analyses.

Thrombin Time

Thrombin Time (TT) reagent is a functional clotting assay measuring the ability of exogenous thrombin to convert fibrinogen to fibrin, followed by fibrin polymerisation and clot detection. Thrombin Time has been designed for easy quality control and should only be used with normal controls.

PT DOAC

PT DOAC is used for functional determination of the extrinsic pathway of the coagulation cascade in patients treated with direct oral anticoagulants (DOACs). A simple and rapid assay for functional determination of DOAC effect has been needed since the introduction of DOACs.

Immunologic assays

D-dimer

D-dimer is a clinically proved, high quality reagent for exclusion of deep vein thrombosis (DVT) and pulmonary embolisms (PE). The reagent has a high sensitivity and high efficiency.

Free Protein S

Free Protein S (FPS) is a latex immunoassay for quantitative determination of free protein S in citrated human plasma. Inherited and acquired protein S deficiency is an important risk factor for deep vein thrombosis (DVT) and pulmonary embolism (PE).

FDP

Green FDP is a latex immunoassay for quantitative determination of fibrin and fibrinogen degradation products (FDP) in citrated human plasma which can be used as an aid in clinical investigations when suspecting abnormal FDP levels. Green FDP is suitable for coagulation analysers operating in the range 500–700 nm.

vWF Antigen

Green vWF Antigen is a latex immunoassay for quantitative determination of vWF Antigen in citrated human plasma which can be used as an aid in diagnosis of von Willebrand disease (vWD). vWD is the most common hereditary bleeding disorder and is caused by either a quantitative or a qualitative defect of vWF.

Chromogenic assays

Antithrombin

Antithrombin (AT) is a liquid, functional, chromogenic assay based on the inhibition of FXa in the presence of heparin. The chromogenic AT assay measures the AT activity (functional AT) by a two-stage method as follows: An excess of FXa is added to the citrated plasma sample pre-diluted with saline and in the presence of heparin.

Protein C

Nordic Biomarker’s Protein C is a chromogenic test for quantitative determination of protein C activity in citrated human plasma which can be used as an aid in diagnosis of protein C deficiency. Protein C deficiencies, hereditary and/or acquired, increases the risk for developing thromboembolic disease.

Controls

Routine controls

Nordic Biomarker’s Routine Controls feature a high stability together with the advantage of including many parameters in one control. As several parameters are included in the same control, one Routine Control can replace up to six competitive products. This will not only reduce cost and work-time but will also unify the quality assessment program for laboratories.

Specialty controls

Nordic Biomarker’s Specialty Controls feature a high stability together with the advantage of including many parameters in one control. As several parameters are included in the same control, one Specialty Control can replace several competitive products. This will not only reduce cost and work-time but will also unify the quality assessment program for laboratories. The Specialty Controls are suitable for the specialty laboratory and are available in normal and abnormal levels.

FDP controls

FDP is a generic name for all fragments formed during plasmin cleavage of fibrin and fibrinogen. FDP Clear Controls consists of human-derived fibrin and fibrinogen degradation products. Intended for quality control of Green FDP reagent.

Buffers, solutions and calibrators

Nordic Biomarker offer all necessary buffers, solutions and calibrators needed to run tests with our reagents on OEM-basis.