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Our wide range of CE-marked Medirox reagent kits are known for their high quality and cover the needs for both routine and specialty coagulation diagnostics. The reagents, together with our CE-marked Medirox calibrator and control kits and their associated products, form a complete solution for the coagulation laboratory.


Product Catalogue


Routine

MRX PT Quick

MRX PT Quick is commonly used for determination of PT in patients administered vitamin K-antagonists and for detection of deficiencies within the extrinsic and common pathways of the coagulation cascade. MRX PT Quick reagent is easy to reconstitute, and calcium is already added to the reagent before lyophilisation.

MRX PT Owren

MRX PT Owren measures the prothrombin time, based on the activity of the vitamin K-dependent coagulation factors; FII, FVII and FX, specifically. MRX PT Owren can be used to monitor warfarin therapy and to evaluate the function of the extrinsic pathway of the coagulation cascade.

MRX APTT

Activated partial thromboplastin time (APTT) is a commonly used screening test for haemostatic defects in the intrinsic and common pathway of the coagulation cascade, as well as the contact activation system. Thus, FII, FV, FVIII, FIX, FX, FXI, FXII, prekallikrein and high-molecular weight kininogen deficiencies can result in a prolonged APTT.

MRX Fib Clauss

MRX Fib Clauss is a functional clotting assay used for quantification of fibrinogen in citrated plasma. MRX Fib Clauss reagent utilises the Clauss technique, where a high concentration of thrombin is added to pre-diluted plasma and the clotting time is measured. The clotting time depends on the level of functional fibrinogen in the sample. MRX Fib Clauss reagent has a large linear range, up to 8 g/L, limiting the number of re-analyses.

MRX Thrombin Time

MRX Thrombin Time (TT) reagent is a functional clotting assay measuring the ability of exogenous thrombin to convert fibrinogen to fibrin, followed by fibrin polymerisation and clot detection. MRX Thrombin Time has been designed for easy quality control and should only be used with normal controls.

MRX Antithrombin

MRX Antithrombin (AT) is a liquid, functional, chromogenic assay based on the inhibition of FXa in the presence of heparin. The chromogenic AT assay measures the AT activity (functional AT) by a two-stage method as follows: An excess of FXa is added to the citrated plasma sample pre-diluted with saline and in the presence of heparin

MRX D-dimer

MRX D-dimer is a clinically proved, high quality reagent for exclusion of deep vein thrombosis (DVT) and pulmonary embolisms (PE). The reagent has a high sensitivity and high efficiency. MRX D-dimer includes three different products designed to match different measuring instruments.

Specialty

MRX Free Protein S

MRX Free Protein S (FPS) is a latex immunoassay for quantitative determination of free protein S in citrated human plasma. Inherited and acquired protein S deficiency is an important risk factor for deep vein thrombosis (DVT) and pulmonary embolism (PE).

MRX Protein C

MRX Protein C is a chromogenic test for quantitative determination of protein C activity in citrated human plasma which can be used as an aid in diagnosis of protein C deficiency. Protein C deficiencies, hereditary and/or acquired, increase the risk for developing thromboembolic disease.

MRX Green FDP

MRX Green FDP is a latex immunoassay for quantitative determination of fibrin and fibrinogen degradation products (FDP) in citrated human plasma which can be used as an aid in clinical investigations when suspecting abnormal FDP levels. Green FDP is suitable for coagulation analysers operating in the range 500–700 nm.

MRX Green vWF Antigen

MRX Green vWF Antigen is a latex immunoassay for quantitative determination of von Willebrand Factor (vWF) Antigen in citrated human plasma which can be used as an aid in diagnosis of von Willebrand disease (vWD). vWD is the most common hereditary bleeding disorder and is caused by either a quantitative or a qualitative defect of vWF.

MRX PT DOAC

MRX PT DOAC is used for functional determination of the extrinsic pathway of the coagulation cascade in patients treated with direct oral anticoagulants (DOACs). A simple and rapid assay for functional determination of DOAC effect has been needed since the introduction of DOACs.

Controls

MRX Routine Controls

MRX Routine Controls feature a high stability together with the advantage of including many parameters in one control. As several parameters are included in the same control, one MRX Routine Control can replace up to six competitive products. This will not only reduce cost and work-time but will also unify the quality assessment program for laboratories. The Routine Controls are suitable for the routine laboratory and are available in normal and abnormal levels.

MRX Specialty Controls

MRX Specialty Controls feature a high stability together with the advantage of including many parameters in one control. As several parameters are included in the same control, one MRX Specialty Control can replace several competitive products. This will not only reduce cost and work-time but will also unify the quality assessment program for laboratories. The Specialty Controls are suitable for the specialty laboratory and are available in normal and abnormal levels.

MRX FDP Clear Controls

FDP is a generic name for all fragments formed during plasmin cleavage of fibrin and fibrinogen. FDP Clear Controls consists of human-derived fibrin and fibrinogen degradation products. Intended for quality control of MRX Green FDP reagent.

Calibrators

MRX Antithrombin Calibrator

MRX Antithrombin Calibrator is intended for calibration of the MRX Antithrombin reagent in IU/mL. The calibrator consists of lyophilised citrated human plasma with a specified level of antithrombin.

MRX Fib Clauss Calibrator

MRX Fib Clauss Calibrator is intended for calibration of the MRX Fib Clauss reagent in g/L. The calibrator consists of lyophilised citrated human plasma with a specified level of fibrinogen.

MRX PT Quick (INR) Calibrator Set

MRX PT Quick (INR) Calibrator Set is intended for calibration of the MRX PT Quick reagent to determine the local International Sensitivity Index (ISI) and the Normal Clotting Time (NCT). The calibrator set consists of six vials with lyophilised citrated human plasma with INR 0.9–6.0.

MRX Free Protein S Calibrator

MRX Free Protein S Calibrator is intended for calibration of the MRX Red Free Protein S and MRX Blue Free Protein S reagents in percent. The calibrator consists of lyophilised citrated human plasma with a specified level of Free Protein S.

MRX FDP Clear Calibrator Set

MRX FDP Clear Calibrator Set is intended for calibration of the MRX Green FDP reagent in µg/mL. The calibrator set consists of five vials with different levels of lyophilised human-derived fibrin and fibrinogen degradation products.

MRX D-dimer DDU Calibrator

MRX D-dimer DDU Calibrator is intended for calibration of the MRX Blue D-dimer, MRX Green D-dimer, and MRX Red D-dimer reagents in ng/mL D-dimer Units (DDU). The calibrator consists of lyophilised citrated human plasma enriched with D-dimer.

MRX D-dimer FEU Calibrator

MRX D-dimer FEU Calibrator is intended for calibration of the MRX Blue D-dimer, MRX Green D-dimer, and MRX Red D-dimer reagents in ng/mL Fibrinogen Equivalent Units (FEU). The calibrator consists of lyophilised citrated human plasma enriched with D-dimer.

MRX Protein C Calibrator

MRX Protein C Calibrator is intended for calibration of the MRX Protein C reagent in percent. The calibrator consists of lyophilised citrated human plasma with specified level of Protein C.

MRX vWF Antigen Calibrator

MRX vWF Antigen Calibrator is intended for calibration of the MRX Green vWF Antigen reagent in percent. The calibrator consists of lyophilised citrated human plasma with specified level of vWF Antigen.

Buffers and solutions

MRX Sodium Chloride Diluent

For dilution (not for reconstitution) of calibrators, controls, and patient samples.

MRX PBS Diluent

For dilution (not for reconstitution) of calibrators, controls, and patient samples.

MRX PT Buffer

MRX PT Buffer is intended for dilution of citrated plasma samples when analysing prothrombin time (PT) using MRX PT Owren assays.

MRX Calcium Chloride

MRX Calcium Chloride is intended to be used to add calcium ions to the citrated human plasma samples in the MRX PT Owren assays and MRX APTT assays.

MRX Laboratory Water

For reconstitution of freeze-dried coagulation-controls and reagents. Contains sodium azide.