MRX Free Protein S
MRX Free Protein S (FPS) is a latex immunoassay for quantitative determination of free protein S in citrated plasma. Inherited and acquired protein S deficiency is an important risk factor for deep vein thrombosis (DVT) and pulmonary embolism (PE). Measurements of free protein S can detect more subtypes of protein S deficiency than measurements of total protein S and has therefore become an important tool in clinical thrombosis investigations. MRX FPS consists of sub-micron sized polystyrene particles coupled to two different monoclonal antibodies specific for protein S. This system is not sensitive to protein S bound to C4BP, and therefore only reacts with free protein S.
MRX FPS includes two different products designed to match different measuring instruments. For instruments operating in the blue wavelength range (400–600 nm) Nordic Biomarker offers MRX Blue Free Protein S. For instruments operating in the red wavelength range (600–800 nm) Nordic Biomarker offers MRX Red Free Protein S.